首页> 外国专利> COMBINATION OF A 5-HT6 RECEPTOR ANTAGONIST AND AN ACETYLCHOLINESTERASE INHIBITOR FOR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE IN A PATIENT SUBPOPULATION CARRYING APOE4 ALLELES

COMBINATION OF A 5-HT6 RECEPTOR ANTAGONIST AND AN ACETYLCHOLINESTERASE INHIBITOR FOR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE IN A PATIENT SUBPOPULATION CARRYING APOE4 ALLELES

机译：5-HT6受体拮抗剂和乙酰胆碱酯酶抑制剂的组合用于治疗Alzheimer患者患者患者患者携带ApoE4等位基因

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摘要

The present invention relates to 5-HT6 receptor antagonists for the treatment of Alzheimer's disease where the Alzheimer's disease patient carries one or two ApoE4 alleles comprising administering an effective dose of a 5-HT6 receptor antagonist to improve or augment the effect of an acetylcholinesterase inhibitor.

机译：本发明涉及5-HT6受体拮抗剂用于治疗阿尔茨海默病的疾病，其中阿尔茨海默病患者携带一种或两种ApoE4等位基因，包括给予有效剂量的5-HT6受体拮抗剂以改善或增加乙酰胆碱酯酶抑制剂的作用。

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公开/公告号EP3630098B1

专利类型
公开/公告日2021-03-24

原文格式PDF
申请/专利权人 H. LUNDBECK A/S;
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申请/专利号EP20180726791
发明设计人 WINDFELD KRISTIAN;
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申请日2018-05-22
分类号A61K31/4045;A61K31/445;A61K31/496;A61K31/505;A61K31/27;A61K31/55;A61K45/06;A61P25/28;
国家 EP
入库时间 2022-08-24 17:53:16

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