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Liver-mimetic device and method for simulation of hepatic function using such device
Liver-mimetic device and method for simulation of hepatic function using such device
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机译:使用这种装置模拟肝功能模拟的肝脏模拟装置
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摘要
A liver-mimetic device and method include a 3D polymer scaffold having a matrix of liver-like lobules with hepatic-functioning particles encapsulated within the lobules. In some embodiments, each liver-like lobule is hexagonal in structure and the matrix is in a honeycomb arrangement. In some embodiments, the hepatic-functioning particles are hepatic progenitor cells. In other embodiments, the hepatic-functioning particles are polymer nanoparticles adapted to capture pore-forming toxins.
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