首页> 外国专利> Composition for preventing or treating dermatitis comprising mixed extracts of Astragalus membranaceus and Schizonepeta tenuifolia

Composition for preventing or treating dermatitis comprising mixed extracts of Astragalus membranaceus and Schizonepeta tenuifolia

机译:用于预防或治疗皮炎的组合物,其包含黄芪膜和Schizonepeta Tenuifolia的混合提取物

摘要

The present invention relates to a composition for the prevention or treatment of dermatitis comprising a complex extract of Astragalus membranaceus and Hyeonggae as an active ingredient, wherein the composition reduces the number of mast cells infiltrating the skin tissue, and NGF (nerve growth factor) and TrkA (tropomyosin receptor kinase A) expression, Raf, MEK (mitogen-activated protein kinase kinase) and ERK (mitogen-activated protein kinase) phosphorylation, and the composition reduces the expression of pro-inflammatory cytokines. And, it has the effect of increasing the expression of anti-inflammatory cytokines, and reducing the expression of Th2 specific cytokines, and thus can be usefully used in the prevention, improvement or treatment of dermatitis.
机译:本发明涉及一种用于预防或治疗皮炎的组合物,其包含黄芪膜和Hyeonggaae作为活性成分的复杂提取物,其中组合物减少了浸润皮肤组织的肥大细胞的数量,以及NGF(神经生长因子)和NGF(神经生长因子)和TRKA(Trobomyosin受体激酶A)表达,RAF,MEK(丝裂剂激活蛋白激酶激酶激酶)和ERK(丝裂原活化蛋白激酶)磷酸化,组合物减少了促炎细胞因子的表达。并且,它具有增加抗炎细胞因子的表达,并降低TH2特异性细胞因子的表达,因此可以有用用于预防,改善或治疗皮炎的抗炎细胞因子。

著录项

  • 公开/公告号KR20210030616A

    专利类型

  • 公开/公告日2021-03-18

    原文格式PDF

  • 申请/专利权人 경희대학교 산학협력단;

    申请/专利号KR1020190111946

  • 发明设计人 양웅모;김미혜;

    申请日2019-09-10

  • 分类号A61K36/481;A23L33/105;A61K36/538;A61K8/9789;A61P17;A61Q19;

  • 国家 KR

  • 入库时间 2024-06-14 21:22:50

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