Pharmaceutical Composition for Preventing or Treating a Disease Caused by Overexpression of MMP Comprising Skullcapflavone Ⅱ and Derivatives Thereof as Active Ingredients

摘要

The present invention relates to a pharmaceutical composition for the prevention or treatment of diseases caused by high expression of various MMPs, including MMP-1, containing skullcapflavone Ⅱ and derivatives thereof as active ingredients, and more specifically, skullcapflavone Ⅱ By inhibiting the expression of MMP-1, etc. even at a concentration of 3 μM or less, it can be effectively used as a pharmaceutical composition for the prevention or treatment of various diseases caused by its high expression, health functional food, and cosmetic composition.