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PDGF receptor beta-binding polypeptide

机译:PDGF受体β结合多肽

摘要

The present invention provides binding polypeptides (e.g., antibodies or fragments thereof) that specifically bind to a target antigen (e.g., a human antigen, e.g., human PDGFRβ) with high affinity. The invention also provides, libraries of binding polypeptides, pharmaceutical compositions, as well as nucleic acids encoding binding polypeptides, recombinant expression vectors and host cells for making such binding polypeptides. Methods of using binding polypeptide of the invention to diagnose and treat disease are also encompassed by the invention.
机译:本发明提供了与靶抗原(例如,人抗原,例如人PDGFRβ)特异性结合的结合多肽(例如,其抗体或其片段,具有高亲和力。本发明还提供了结合多肽,药物组合物的文库,以及编码结合多肽的核酸,重组表达载体和宿主细胞,用于制备这种结合多肽。本发明还包括使用本发明结合多肽的方法诊断和治疗疾病。

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