Diagnosis method, information provision method, composition and kit of early periodontitis using S100 protein in saliva

摘要

The present invention comprises the steps of collecting saliva separated from the subject; Analyzing the expression levels of S100A8 and S100A9 proteins from the saliva; And when the S100A8 protein expression level in the saliva is higher than the S100A8 protein expression level in the saliva of the normal control, and the S100A9 protein expression level in the saliva is lower than the S100A9 protein expression level in the saliva of the normal control group, associating the subject with periodontitis. It relates to a method for diagnosing periodontitis and a method for providing information for diagnosing periodontitis, and a composition for diagnosing periodontitis comprising a formulation for measuring the expression levels of S100A8 and S100A9 proteins, and a periodontitis diagnosis kit comprising the composition for diagnosing periodontitis can be provided.