首页> 外国专利> Peptides derived from transient receptor potential cation channel subfamily M member 1 (TRPM1), complexes comprising such peptides bound to MHC molecules

Peptides derived from transient receptor potential cation channel subfamily M member 1 (TRPM1), complexes comprising such peptides bound to MHC molecules

机译:衍生自瞬时受体电位阳离子通道亚家族M构件1(TRPM1)的肽,包含与MHC分子结合的这种肽的复合物

摘要

The present invention relates to novel peptides derived from Transient receptor potential cation channel subfamily M member 1 (TRPM1), complexes comprising such peptides bound to recombinant MHC molecules, and cells presenting said peptide in complex with MHC molecules. Also provided by the present invention are binding moieties that bind to the peptides and/or complexes of the invention. Such moieties are useful for the development of immunotherapeutic reagents for the treatment of diseases such as cancer.
机译:本发明涉及从瞬时受体电位阳离子通道亚家族M构件1(TRPM1)的新型肽,包含所述肽与重组MHC分子结合的络合物,以及将所述肽的细胞与MHC分子呈现复合物。本发明还提供了与本发明的肽和/或复合物结合的结合部分。这种部分可用于开发免疫治疗试剂,用于治疗癌症如癌症。

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