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Device and method for determining the action of active ingredients on nematodes and other organisms in aqueous tests

机译:用于确定活性成分对线虫和其他生物的作用的方法和方法

摘要

The invention relates to a device (1) and a method for determining the action of active ingredients on nematodes and other organisms in aqueous tests. The device (1) according to the invention comprises a holder (13) for a cell culture plate (30) having multiple wells (31) in which the nematodes can be filled with the active ingredients, said cell culture plate (30) having a bottom side (33), a top side (32) and also side walls extending between bottom side (33) and top side (32), a camera (11) which is used to record images of preferably the bottom side (33) of the cell culture plate (30), a lighting mechanism (14) having at least a first light source (15) which illuminates the cell culture plate (30), there being arranged between the first light source (15) and a first side wall (34) of the cell culture plate (30) in the installed state a first optical unit which directs the light of the first light source (15) through the first side wall (34) in the direction of the bottom side (33) of the cell culture plate (30). The method according to the invention makes it possible to simultaneously investigate many active ingredients within a very short time.
机译:本发明涉及一种装置( 1 / b>)和用于测定在水性试验中的线虫和其他生物上的活性成分的作用的方法。根据本发明的装置( 1 )包含具有多个孔的细胞培养板( 30 )的保持器( 13 / b>)( 31 )其中线虫可以用活性成分填充,所述细胞培养板( 30 )具有底侧( 33 ),顶部侧面( 32 )以及在底侧( 33 / b>)和顶侧( 32 )之间延伸的侧壁,相机( 11用于记录细胞培养板( 30)的底侧( 33 / b>)的图像的图像,照明机构( 14具有至少一个第一光源( 15 15 ),其布置在第一光源之间( 30 )的第一侧壁( 34 )的第一光学单元引导第一光源( 15 )通过第一侧壁( 34 )沿底侧的方向( 33 )细胞培养板( 30 )。根据本发明的方法使得可以在很短的时间内同时研究许多活性成分。

著录项

  • 公开/公告号US10948481B2

    专利类型

  • 公开/公告日2021-03-16

    原文格式PDF

  • 申请/专利权人 BAYER AKTIENGESELLSCHAFT;

    申请/专利号US201916682666

  • 发明设计人 FRANCO FOIS;MICHAEL HARNAU;KLAUS OCHMANN;

    申请日2019-11-13

  • 分类号G01N33/50;G01N21/25;G06T7/254;G06K9/36;G06T5/20;G06T7;

  • 国家 US

  • 入库时间 2024-06-14 21:22:18

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