Aptamer passing through blood-brain barrier and its application

摘要

The present invention relates to an aptamer that passes through the blood-brain barrier (BBB), and relates to an application of such an aptamer to a complex combined with a substance that selectively binds to a target substance present in the brain, and the like, the present invention The aptamer of and the complex combined with the aptamer can be used as a positron emission tomography (PET) radiographic contrast agent to diagnose Alzheimer's disease or Parkinson's disease at an early stage. It can be used as a radiographic material that can be imaged on, and can be used as a treatment for degenerative brain diseases.