STRAIN ASIA-1 2356/14/2018 OF THE FMD VIRUS APHTAE EPIZOOTICAE OF ASIA-1 TYPE FOR MANUFACTURE OF BIOLOGICAL PRODUCTS FOR THE DIAGNOSIS AND SPECIFIC PREVENTION OF FMD TYPE ASIA-1

摘要

FIELD: biotech.;SUBSTANCE: invention relates to a new strain of foot and mouth disease Aphtae epizooticae of Asia 1 type, Picornaviridae family, genus Aphthovirus, deposited in the collection of FSBI "ARRIAH" under registration number: No 176 - dep / 19-66 - GKShM FSBI "ARRIAH" strain Asia-1 No 2356 / 14/2018 of FMD virus. The presented strain is reproduced in continuous cultures of kidney cells of the Siberian mountain ibex (PSGK-30), in a continuous culture of pig kidney cells IB-RS-2 and in a continuous culture of kidney cells of the Syrian hamster BHK - 21, within 20-24 hours of incubation; virus yield, assessed by the cytopathic effect in these cell cultures, reaches values ​​from 5.25-7.00 lg TCD₅₀/cm³, maintaining the original characteristics when passaged in cell cultures for 5-10 passages. EFFECT: presented strain can be used to control the antigenic activity of FMD vaccines and for the manufacture of biological products for the diagnosis and specific prevention of FMD of Asia 1 type.;1 cl, 1 dwg, 6 tbl