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Structure for retinal cell culture using 3D bioprinting and Uses thereof

机译:使用3D生物监测和用途的视网膜细胞培养结构

摘要

The present invention relates to a structure for culturing retinal cells to which 3D bioprinting technology is applied, and to its use, and specifically, a method of manufacturing a structure for culturing retinal cells and a structure for culturing retinal cells prepared therefrom, and an ex vivo retina model using the same It relates to a method of manufacturing and screening a retinal disease therapeutic agent. The retinal cell culture construct can provide an ex vivo retina model having morphological and functional characteristics similar to that of the retina in vivo, and this ex vivo retina model has a very high correspondence with pathological phenomena occurring in vivo to prevent retinal diseases. It may be usefully used for screening a therapeutic agent for retinal diseases that can be improved or treated.
机译:本发明涉及用于培养3D生物监测技术的视网膜细胞的结构,以及其使用,具体地,制造用于培养视网膜细胞的结构和用于培养其制备的视网膜细胞的结构,以及EX使用相同的体内视网膜模型涉及一种制造和筛选视网膜疾病治疗剂的方法。视网膜细胞培养构建体可以提供具有类似于体内视网膜的形态学和功能特性的离体视网膜模型,并且该exVivo视网膜模型与体内发生的病理现象具有非常高的对应性,以防止视网膜疾病。它可以有用用于筛选可改善或处理的视网膜疾病的治疗剂。

著录项

  • 公开/公告号KR102224115B1

    专利类型

  • 公开/公告日2021-03-09

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR1020200003898

  • 发明设计人 김홍균;강현욱;손정현;김경하;

    申请日2020-01-10

  • 分类号C12N5/079;B33Y70;C12N5/071;

  • 国家 KR

  • 入库时间 2022-08-24 17:35:05

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