The present invention is a symptom-genetic variation correlation analysis unit for calculating a symptom-related genetic variation correlation indicating the degree of influence of the genetic variation on a symptom; And a disease is defined as a combination of symptoms, and a genetic variation-related disease correlation is calculated using the symptom-related genetic variation correlation for each symptom defining a disease, indicating the degree to which the genetic variation causes the disease. It provides a disease-causing genetic mutation discovery system including a mutation-disease correlation analysis unit.
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