PHARMACEUTICAL COMPOSITION FOR TREATING METABOLIC DISEASES COMPRISING EXOSOME DERIVED FROM MILK AS AN ACTIVE INGREDIENT

摘要

The present invention comprises exosomes derived from milk as an active ingredientIt relates to a pharmaceutical composition for the treatment of metabolic diseases. Specifically, the exosomes derived from milk of the present invention contain mi-155 and mi-375, which are known to have antidiabetic activity, and to IRS-1 and GLUT-4 proteins, which are factors that promote insulin signaling. By inhibiting the expression of the mRNA for C/EBPβ and PDK4 protein, which are factors that inhibit insulin signaling while promoting the expression of the mRNA for insulin, it can be usefully used in the treatment of metabolic diseases.