Quantitative method of Hex4, lyso-GM1, Fuc-GlcNAc-Asn, and lyso-glucoside contained in cerebrospinal fluid

摘要

PROBLEM TO BE SOLVED: To provide a method for quantifying Hex4, lyso-GM1, Fuc-GlcNAc-Asn, or lyso-glucotide in the brain. A method for quantifying Hex4, lyso-GM1, Fuc-GlcNAc-Asn, or lyso-sulfataide contained in cerebrospinal fluid, in which an internal standard substance is added to a solution containing the cerebrospinal fluid. A method comprising a step of subjecting a solution containing cerebrospinal fluid to which the internal standard substance has been added to liquid chromatography to obtain an eluate, and a step of subjecting the eluate to mass spectrometry. .. [Selection diagram] FIG. 7