NONINVASIVE DEEP BRAIN STIMULATION (DBS) USING X-RAY-EXCITED OPTICAL LUMINESCENT (XEOL) NANOMATERIALS (NANOSCINTILLATORS)

摘要

A method for performing deep tissue stimulation using radiation-enabled optogenetics including introducing a plurality of nanoscintillators into a region with light sensitive cells, and targeting the nanoscintillators with a primary radiation to cause the nanoscintillators to emit optical energy. The light sensitive cells having an optically active wavelength range, and the emitted optical energy having a wavelength in the optically active wavelength range. In particular, introducing X-ray excited optical luminescent nanomaterials to a tissue region and controlling electrical activity in cells containing opsins.