The present invention relates to a composition for preventing or treating neurological diseases comprising a Wasong extract or a fraction thereof, and more particularly, the fraction fractionated from Wasong showed a high total phenolic compound content, and in particular, ABTS, DPPF radical scavenging activity and FRAP and lipid peroxide production inhibitory activity, improves the cell survival rate against the death of nerve cells due to hydrogen peroxide, and has the effect of protecting the cell membrane damage of nerve cells, it can be used as a pharmaceutical composition and health functional food for preventing or treating neurological diseases.
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