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Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto
Bone morphogenetic protein pathway activation, compositions for ossification, and methods related thereto
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机译:骨形态发生蛋白途径活化,骨化组合物,以及与其相关的方法
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摘要
The disclosure relates to compounds and compositions for bone formation, fracture treatment, bone grafting, bone fusion, cartilage maintenance and repair, and methods related thereto. In certain embodiments, the disclosure relates to compositions comprising one or more compound(s) disclosed herein derivatives, or salt thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement. In certain embodiments, compounds disclosed herein are useful for managing obesity and diabetes or other metabolic syndromes by modulation of brown fat.
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