A method for obtaining combinations of tisemicarbazone from pyridine-3-aldehyde and/or from pyridine-4-aldehyde with hydrazine from isonicotinic acid (Machine-translation by Google Translate, not legally binding)

摘要

Method for obtaining combinations of thiosemicabazone of pyridin-3-aldehyde and/or pyridin-4-aldehyde with isonicotinic acid hydrazide to achieve an increased synergistic effect characterized essentially by the fact that to an amount of thiosemicarbazone of pyridin-3 -aldehyde and 7 or pyridin-4-aldehyde. Defined by being derived from doses that have an optimum clinical effect based on 1 to 3 mg per kg of body weight, hydrazide of isonicotinic acid is incorporated in an amount derived from a dose per kg of body from 4 to 15 mg, corresponding to the defined proportions of those indicated components to those from 1 to 3 parts of thiosemicarbazone of the aforementioned heterocyclic aldehydes with respect to 4 to 15 parts of isonicotinic acid hydrazide. (Machine-translation by Google Translate, not legally binding)