Procedure for the production of a series of soluble derivatives in the water and injectives of tetracycline. (Machine-translation by Google Translate, not legally binding)

摘要

Process for the production of a series of water-soluble derivatives and injectables of tetracycline, represented by the salts of tetracycline-methyl-N1, N1-diethylene amine-biguanide, having the formula: ** (See formula) ** wherein R is the monovalent radical of an organic or inorganic acid9 characterized in that the dicyandiamide is reacted with piperazine in an acid medium, and because the product thus obtained is reacted with tetracycline in the presence of formaldehyde, thus achieving the desired product. (Machine-translation by Google Translate, not legally binding)