A procedure for dissolving medicines containing one or several atoms of nitrogen basic reaction in pharmacologically useful solvents. (Machine-translation by Google Translate, not legally binding)

摘要

A process for dissolving medicaments containing one or several nitrogen atoms of basic reaction, in pharmacologically usable solvents or solvent mixtures, characterized in that aryl sulfonic acids, optionally substituted by alkyl groups, are used as intermediate dissolution agents or solubilizing agents. Of low molecular weight, hydro-aromatic sulphonic acids optionally substituted by alkyl groups, terpenesulfonic acids, camphorsulfonic acids or sulfuric acid semiamides of the general formula ** (see formula) ** Wherein y are the same or different and denote hydrogen atoms, phenyl or phenalkyl groups having 1 to 5 carbon atoms in the alcohol group, or straight or branched low molecular weight alkyl groups, which may also be closed to form a ring which eventually contains a new oxygen or nitrogen atom. (Machine-translation by Google Translate, not legally binding)