process for the preparation of derivatives of n, n '- dialcoxy - dialcoyles or with acid, dibenzyloxyalcoyles disubstitues 5.5

摘要

1276387 N,NSP1/SP-Hydrocarbyloxyalkyl-barbituric acids KENDALL CO 3 Feb 1970 [4 Feb 1969 9 Jan 1970] 5177/70 Heading C2C N,NSP1/SP-Dialkoxyalkyl or N,NSP1/SP-dibenzyloxyalkyl-5,5-disubstituted barbituric acids are obtained by contacting a 5-R,5-RSP1/SP-substituted barbituric acid, in which R and RSP1/SP are a phenyl and an ethyl respectively, or R and RSP1/SP may each independently denote a C 2-5 alkyl or alkenyl group or a C 5-7 cycloalkenyl group with NaH, KH, LiH, LiOH or KO-t-Bu, or a mixture of two or more thereof, in a solvent for the barbituric compound which is inert with respect to the reactants, and subsequently contacting the mixture with a haloalkyl alkyl ether or a haloalkyl benzyl ether, the molar ratio of alkaline compound : barbituric compound being at least 2 : 1 and the molar ratio of ether : barbituric compound being at least 2 : 1.