Di:alkyl aryl phosphoro:thioate prodn. - from phenol and phosphoro:thio:chloridate in presence of water and tert. amine

摘要

Prodn. of O,O-dialkyl O-aryl phosphorothioates (I) is effected by reacting an O,O-dialkyl phosphorothiochloridate (II) with a water-contg. phenol or phenoxide in an aq. or aq.-organic medium at 20-100 deg.C. in the presence of a water-soluble tert. amine catalyst. Pref. amines are NEt3 and picoline, pref. used in an amt.of 0.02-0.05 mole per mole of (II). Mixing of the phases may be improved by saturating the aq. phase with alkali(ne earth) metal salts and/or adding a surfactant, e.g. an alkali metal 12-16C alkanesulphonate. Cpds. of type (I) are useful as insecticides. Use of tert. amine catalysts increases the yield of (I), e.g. to 87.5-95%.