Indolyl vindolines intermediates for alkaloids

摘要

Indolyl vindolines (I) where alk = lower alkyl (1-3 C atoms) R1 = H, alk, or CHO R2, R3 = H or COalk R7 = NHNH2 or Oalk Z = -CH2CH2-, or -CH=CH- R = where R4, R5, R6 = H or alk and R4, R5 may be an alkylene (2 or 3 C atoms). Intermediates for the synthesis of alkaloids in the vinblastine class.