Cpds. R1=H or 1,2-CH2- R2=3-keto DELTA4, 3-Keto DELTA1,4, 3-keto-DELTA4,6 3-keto-DELTA1,4,6, 3-OR-DELTA4, 3-OR-DELTA4,6, 3-OR-DELTA3,5, or 3-OR'-DEL

摘要

Cpds. R1=H or 1,2-CH2- R2=3-keto DELTA4, 3-Keto DELTA1,4, 3-keto-DELTA4,6 3-keto-DELTA1,4,6, 3-OR-DELTA4, 3-OR-DELTA4,6, 3-OR-DELTA3,5, or 3-OR'-DELTA2,4,6 where R=H, alkyl, or acyl, and R1=alkyl or acyl; R3=H, halogen, or (1-6C) alkyl R4=H or 6,7-CH2- R5=H, OH, Oalkyl, or Oacyl R6=MeCO, -CO.CH2OH opt. esterified or acylated, or -CH(OH)Me R7=(2-3C) alkyl or (2-3C) alkenyl R8=3-keto-DELTA4, 3-keto-DELTA1,4, or 3-keto-DELTA1,4,6 (I)-Gestagens (esp. R7=Et), contraceptives, and pregnancy-maintaining cpds. (II)-Intermediates for (I).