derivatives of benzofuran derivatives and medicines based on the benzofuran

摘要

1314922 2-Nitrobenzofurans AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE 19 April 1971 [24 March 1970 28 Aug 1970] 25041/71 Heading C2C The invention comprises compounds of formula wherein RSP1/SP is H or C 1-6 alkyl, and RSP2/SP, RSP3/SP are each H, halogen or C 1-6 alkyl, provided that at least one of RSP1/SP, RSP2/SP, and RSP3/SP is other than hydrogen, and a process for making them by reacting the corresponding 2-unsubstituted benzofuran with concentrated HNO 3 in HOAc or Ac 2 O. II are prepared by cyclization of 2,4,5-RSP1/SPCO(RSP2/SP)(RSP3/SP) C 6 H 2 OCH 2 CO 2 H which are in turn obtained from their ethyl esters. Therapeutic compositions for oral or topical administration comprise compounds of the above formula (to which the process does not apply), which are active against organisms and parasites.