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2-(2-(1-substd-3,5-dimethyl-pyrrol-3yl) vinyl - 6-dimethylaminoquinoline methyl halides

机译:2-(2-(1-亚甲基-3,5-二甲基-吡咯-3基)乙烯基-6-二甲基氨基喹啉甲基卤化物

摘要

Title cpds. of formula (where R = alkyl, phenyl X = Cl, Br, I) are prepared in improved yield by reacting 6-dimethylamino-quinolidinomethyl halide with 2,5-dimethyl-1R-3-pyrrole carboxaldehyde using a 50% aq. soln. of zine chloride as catalyst. Their salts with nitroimidazoacetic acids are also prepared. The cpds. are active against Enterobius and Strongloydis nematodes.
机译:标题cpds。式(其中R =烷基,苯基X = Cl,Br,I)的通式(50)是通过使6-二甲基氨基喹啉亚甲基卤化物与2,5-二甲基-1R-3-吡咯甲醛经50%碳酸氢钠水溶液反应制备的。 soln。氯化锌作为催化剂。还制备了它们与硝基咪唑乙酸的盐。 cpds。对Enterobius和Strongloydis线虫有活性。

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