Cytostatic Schiff bases. Compounds of formula: (where X, Y = H, lower alkyl, lower alkoxy; W = H, lower alkoxy; Z = -NHCOOR or oxazolidin-2-one (1); R = opt. halo substd. lower aliphatic) are prepared by reaction of the 4 bis(2 chloroethyl)-amino benzaldehyde with a W, Z substd. aniline in the presence of a dehydrating agent.
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机译:静息席夫碱。式的化合物:(其中X,Y = H,低级烷基,低级烷氧基; W = H,低级烷氧基; Z = -NHCOOR或恶唑烷-2-酮(1); R =优选为卤素取代的低级脂族基)通过使4-双(2-氯乙基)-氨基苯甲醛与W,Z取代基反应制备。苯胺在脱水剂的存在下。
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