method for preparation of pharmaceutical preparations with soothing effect on the basis of 5 - phenyl - 1.4 - benzodiazepine derivatives and process for preparation of 5 - phenyl - 14 - benzodiazepine derivatives suitable for use in this method.

摘要

1374475 Benzodiazepines TAKEDA YUKUHIN KOGYO KK 29 Oct 1971 [30 Oct 1970] 50347/71 Heading C2C Compounds of the general formula (R=H, C 1 -C 3 alkyl; X=O, NH; Y=CH 2 CH 2 or CH 2 CH 2 CH 2 optionally substituted by C 1 -C 3 alkyl; rings A, B optionally bear one or more substituents selected from halogen, NO 2 , CF 3 , alkyl, alkoxy), and their salts are prepared by reacting a compound of the formula (Z=halogen) with HX-Y-NH 2 , optionally followed by salt formation. The above compounds are tranquilizers, muscle relaxants, sedatives, sleep inducers and anti-convulsants, and may be administered in the form of pharmaceutical preparations containing them in association with a carrier.