Method of production of new d-18-methyl-17-alkinyl-4-eastern-17-ols

摘要

Steroid derivs with gestagenic and anti-ovulation action Cpds. are of formula (where R1 is H or acyl; and R2 is H, Cl, or lower (un) satd. aliphatic gp). Preferred cpds. are d-18-methyl-17 alpha-ethinyl-4-oestrene-17 beta-ol and its acetate, and d-17 beta-hexanoyloxy-18-methyl-17 alpha-ethinyl-4-oestrene.