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4-alkyl (or cycloalkyl) benzoylmethyl anthranilates - - with spasmolytic, antiinflammatory and analgesic activity
4-alkyl (or cycloalkyl) benzoylmethyl anthranilates - - with spasmolytic, antiinflammatory and analgesic activity
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机译:4-烷基(或环烷基)苯甲酰基甲基邻氨基苯甲酸酯--具有解痉,消炎和镇痛作用
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摘要
Cpds. are of formula: where A is =CH-CH=CH-, =N-CH=CH-, =CH-CH=N-, =N-CH=N-, or =CH.S-; R1 is an opt. alkyl or halogen substit. on a C-atom; R2 is an opt. alkyl, alkoxy, or alkylthio substit. on a C atom; R3 is =1, alkyl, CF3, halogen, NO2, alkoxy, alkylthio, alkoxymethyl, alkylthiomethyl, or acyloxymethyl gps; R4 = alkyl (C1-C10), cycloalkyl (C5-C6); R5 = opt. halogen substit. Y = =N-, =CH-, Z = =N-, =CH-, or Y and Z together may be CH2, may be a single or double bond. Prepd by esterification of the anthranilic acid chloride or bromide with the appropriate benzoylmethanol in an inert solvent, opt. in presence of an acid-binding agent.
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