D-and l-isomers of 6h, 7h, cis-7-amino-3-aminomethyl cef -3 - em-4-car acid-gamma- lactams

摘要

Title cpds. of formula (I): (where R2 is H, alkyl or aryl) are prepd. from trityl derivs. of formula (II) by (i) resolution of the 1-sparteine diastereoisomers; (ii) ring closure with dicyclohexylcarbodiimide; (iii) detritylation with HCl gas in MeNO2.