Indium 113m labelling of transferrin - by mixing a radioactive indium eluate amd amino acid with transferrin soln

摘要

Human transferrin is labelled with In-113m by (a) collecting an acid eluate of an In-113m-generator (pref of activity 0.1-50 m curies/ml. in 0.01-0.2 N HCl) (b) dilating with 0.05-0.50N NaOH contng. 0.01-0.10 equiv. of aminoacid (pref. glycine) (c) mixing the resulting soln (pH 3-4) with a soln of transferrin. The final prodt. has pH 6-7.5 and is made isotonic with NaCl. A bacteriostat may also be added. The yield of labelled product is approx. 100%.