A procedure for the preparation of hepta and octapeptides of formula: **(See formula)** where R is hydrogen, succinyl, L-aspartyl, sarcosyl, L-seryl, succinamyl, L-propyl, glycyl, D- or L-asparaginyl; R1 is a residue of L-alenin, L- or D-leucine, glycine, L-isoleucine or p-alanine; and R2 is L-valyl, L-isoleucil or L-alanyl, whose procedure consists of: (a) reacting a blocked amino acid attached to a support; (b) separating the blocking group under acidic conditions, followed by neutralization, the product of each of these stages being subjected to solvent washes; (c) introducing a proximal blocked amino acid residue, employing a peptide bond forming agent, in the presence of a solvent or other appropriately activated blocked amino acid, followed by said solvent washes; (d) repeating steps (b) and (c) until the compounds shown above are formed in the blocked state; and (e) removing the blocking groups by cleavage agents. (Machine-translation by Google Translate, not legally binding)
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