Distillative prepn of dimethylformamide dimethyl acetal - - by reaction of dmf,dimethyl-sulphate and methanol-sodiummethylate

摘要

Distillative prepn. of dimethylformamide dimethylacetal (I) is characterised in that a mixt. resulting from reaction of DMF, Me2SO4 and MeOH-sodiummethalate soln. is rapidly and vigorously stirred and distilled at 65-70 degrees C; MeOH is added dropwise into the distillation still, as trailing medium, after the main portion of the distillation product has passed; and the resulting MeOH/(I) mixture is then fractionated. (I) is used as synthesis aid in alkylation and formylation reactions.