N - substituted amino acids with actions against viruses, inflammations and / or tumors

摘要

1351437 Medicines comprising amino acid derivatives AJINOMOTO CO INC 18 Aug 1972 [19 Aug 1971 (3)] 38748/72 Heading A5B [Also in Division C2] A therapeutic composition suitable for oral or parenteral administration comprises a pharmaceutical carrier and as the active ingredient novel N-#-naphthylaminomethyl-leucine, N-#- naphthylaminomethyl urethane, N-furfurylaminomethyl-phenylalanine, . N-furfuryl-4-nitrophenylalanine, N- 2 -fluorenesulphonylmethionine, N-2-fluorenesulphonyl-phenylalanine, N- ethylcarbanunomethyl-isoleucine, N-#-naphthylaminiomethyl-threonine; N-9-fluorenylacetylphenylalanine, N-myristoyl-isoleucine or N-#- naphthalenesulphpnyl-tryptophan. or a pharmaceutically acceptable salt thereof. The above composition may be in a unit dosage form and in this form the invention also includes a therapeutic composition comprising a pharmaceutical carrier and as the active ingredient N-benzylvaline, N-lauroyl-leucine' or N-propionylvaline or. a pharmaceutically acceptable salt thereof. The compositions are useful for combatting infection with influenza virus, as anti-inflammatory agents or as anti-tumour agents.