ABSTRACT OF THE DISCLOSUREThe present invention provides an analysis procedurein which reagents and a sample solution in an optically-thinlayer chemically react to produce a reaction product that is aknown measure of a constituent in the sample solution. Use ismade of fibrous sheets which are essentially non-absorbingand uniform in structure within and contiguously beyond thereaction site to generally eliminate the need of using confinedtest sites. The layer is examined under electromagneticradiation with a sensing means that responds in a linear mannerto the concentration of a selected constituent-manifestingproduct of the reaction. The invention enables such measurementsto be made repeatedly with precision even when the spatialdistributions of the material being analysed and of the reaction-producing reagents over the thin layer both are not uniformand differ from one another, provided that the distributions arethe same for successive samples.
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