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NOVEL 16-METHYLENE-9{62 , 10{60 -STEROID COMPOUNDS, PHARMACEUTICAL PREPARATIONS WHICH CONTAIN THE NOVEL COMPOUNDS AS ACTIVE INGREDIENTS, AND METHODS OF PRODUCING THE SAID COMPOUNDS AND PREPARATIONS
NOVEL 16-METHYLENE-9{62 , 10{60 -STEROID COMPOUNDS, PHARMACEUTICAL PREPARATIONS WHICH CONTAIN THE NOVEL COMPOUNDS AS ACTIVE INGREDIENTS, AND METHODS OF PRODUCING THE SAID COMPOUNDS AND PREPARATIONS
The invention relates to novel 16-methylene-17 alpha -acyloxy (or etherified hydroxy)-9 beta , 10 alpha -steroid compounds of the pregnane series which have an exceptionally high endocrinological activity, such as a very strong progestational and anti-ovulatory activity. After the compounds have been worked up into pharmaceutical preparations they may be used inter alia as contraceptives or for maintaining pregnancy. Highly active substances according to the invention are, for example, 6-chloro-16-methylene-17 alpha -hydroxy-9 beta , 10 alpha -pregna-4,6-diene-3,20-dione 17-acetate and 6-fluoro-16-methylene-17 alpha -hydroxy-9 beta , 10 alpha -pregna-4,6-diene-3,20-dione 17-acetate.
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