Process for the preparation of 7-(D-2-amino-2-(1,4-cyclo-hexadienyl) acetamido) desacetoxycephalosporanic acid and 7-(D-2-amino-2-(1,4-cyclohexadienyl) acetamido) cephalosporanic acid

摘要

Processes for the preparation of 7-[D-2-Amino-2-(1,4-cyclohexadienyl)acetamido]desacetoxycephalosporanic acid and 7-[D-2-Amino-2-(1,4-cyclohexadienyl)acetamido]cephalosporanic acid are described utilizing N-(2,2,2-trichloroethyloxy- or t-butoxy-carbonyl)-D- alpha -dihydrophenylglycine and 7-aminodesacetoxycephalosporanic acid, 2,2,2-trichloroethyl or t-butyl ester or 7-aminocephalosporanic acid, 2,2,2-trichloroethyl or t-butyl ester, respectively.