A process for the preparation of 7-chloro-1- (2-diethylaminoethyl) -5- (2-fluorophenyl) -1,3-dihydro-2H-1,4-benzodiazepin-2-one, monohydrochloride.

摘要

1331823 Benzodiazepine F HOFFMANNLA ROCHE & CO AG 23 Nov 1971 [8 June 1971] 54368/71 Heading C2C 7 - Chloro - 1 - (2 - diethylaminoethyl) - 5 - (ofluorophenyl) - 1,3 - dihydro - 2H - 1,4 - benzodiazepin - 2 - one hydrochloride is prepared from the base and/or dihydrochloride. The compound is useful in the treatment of sleep disturbances, and may be administered in the form of pharmaceutical preparations containing it in association with a carrier. Reference has been directed by the Comptroller to Specification 1,040,548.