method for preparing a medicine with blood pressure lowering effect.as a veretherd which active compound 1 - (3 - hydroxypropyl) - 4 - phenyl - or - 4 - (fenylalkyl) - piperazine derivative is included.according to this method, the obtained product and method for preparing the active connection.

摘要

1-[3-(5,6,7,8-TETRAHYDRONAPHTH-1-YLOXY)-PROPYL]-PIPERAZINE DERIVATIVES OF THE FORMULA WHEREIN A is hydrogen or hydroxyl; X is hydrogen or halogen or alkyl, alkoxy, alkylthio, trifluoromethyl, hydroxyl, nitro, amino, acylamino (i.e., alkanoylamino) or alkylsulfonylamino; and N IS 0, 1 OR 2; AND THE PHARMACOLOGICALLY COMPATIBLE SALTS THEREOF; EXHIBIT OUTSTANDING BLOOD PRESSURE DEPRESSING ACTIVITY, I.E., POSSESS ANTIHYPERTENSIVE PROPERTIES.