SERUM LIPID LOWERING COMPOUNDS AND THEIR PREPARATION

摘要

Compounds of the general formula AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, WHEREIN X is -O- or -NH-; RO is H, F, Cl, Br or OCH3; R1 and R2 are the same or different and selected from the group consisting of H and alkyl groups having 1-3 carbon atoms; R3 is H or an alkyl group having 1-3 carbon atoms; Ro and the side-chain containing the radicals R1, R2 and R3 being placed on the same or different benzene ring. Pharmaceutical preparations containing these compounds are useful in a method for lowering the serum lipid concentration in mammals, including man. These same preparations are also useful for the combined lowering of serum cholesterol and triglyceride concentrations.