STABILIZED MOLDED SUBLINGUAL NITROGLYCERIN TABLETS

摘要

Pharmaceutical compositions containing minor proportions of nitroglycerin and a non-volatile, water-soluble solvent in combination with a major proportion of a solid, water-soluble pharmaceutical carrier. Those compositions, in the form of tablets suitable for sublingual administration, can be produced by wetting a substantially dry mixture of the nitroglycerin and the solid, water-soluble pharmaceutical carrier with a solvent mixture containing a non-volatile, water-soluble solvent and a volatile solvent, forming the wetted mixture into tablets, and removing the volatile solvent.