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Hydroxamino-substd. oxazolobenzodiazepines - sedatives, muscle relaxants and anti-convulsants
Hydroxamino-substd. oxazolobenzodiazepines - sedatives, muscle relaxants and anti-convulsants
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机译:羟基氨基取代。恶唑苯并二氮杂卓-镇静剂,肌肉松弛剂和抗惊厥药
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摘要
The dizepines are of formula (I) (where R1 is H, lower alkyl, 4-10C cycloalkyl-lower alkyl, lower alkoxy-lower alkyl, hydroxy-lower alkyl or di-loweralkylamino-lower alkyl; R2 and R3 are H or lower alkyl and R4 is H or halogen) and their addn. salts are by selective redn. of the corresp. nitro cpd. (I) are sedatives, muscle relaxants and anti-convulsants, the daily dosage being 2-200 mg.
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机译:二氮杂为式(I)(其中R 1为H,低级烷基,4-10C环烷基-低级烷基,低级烷氧基-低级烷基,羟基-低级烷基或二低级烷基氨基-低级烷基; R 2和R 3为H或更低烷基和R 4是H或卤素)及其加成基。通过选择性还原盐。相应的硝基cpd (I)是镇静剂,肌肉松弛剂和抗惊厥药,每日剂量为2-200毫克。
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