A process for preparing 2-hydroxyethylestere of 2-quinoxalinecarboxylic acid-1,4-dioxides by transesterification of a corresponding 2-alkyl ester with ethylene glycol in the presence of a basic catalyst.

摘要

1374360 Preparation of quinoxaline-di-N- oxide derivatives PFIZER Inc 24 April 1972 [6 Aug 1971] 18984/72 Heading C2C The compounds I in which X is 6- or 7- H, Cl, Br, CH 3 , CH 3 O or CF 3 ; are prepared by reaction of a compound II in which R is 1-4C alkyl, with ethylene glycol in the presence of oxygen and, as catalyst, Ca(OH) 2 or Ba(OH) 2 at 30-50‹ C.