首页> 外国专利> method for the preparation of 5 - oxo - 5h - diben - cycloheptenen (a.d.). method for preparation of pharmaceutical preparations, and thus manufactured objects.

method for the preparation of 5 - oxo - 5h - diben - cycloheptenen (a.d.). method for preparation of pharmaceutical preparations, and thus manufactured objects.

机译:5-氧代-5h-二苯甲酸酯-环庚烯的制备方法(公元)。药物制剂的制备方法,以及由此制备的物品。

摘要

2-Substituted-5-oxo-5H-dibenzo[a,d]cycloheptenes represented by the following formula: IMAGE where R' is hydrogen, alkyl having 1 to 12 carbon atoms, or IMAGE where n is an integer from 2 to 4, inclusive, and R4 and R5 are independently lower alkyl having 1 to 6 carbon atoms or together R4 and R5 and the nitrogen atom to which they are attached form a heterocyclic ring having 5 or 6 total ring atoms; and the pharmaceutically acceptable salts thereof. The compounds are useful in the treatment of auto-immune diseases and allergic reactions.
机译:下式表示的2-取代的5-氧代-5H-二苯并[a,d]环庚烯:其中R'是氢,具有1至12个碳原子的烷基,或其中n是一个整数R 4和R 5分别独立地为碳数为1〜6的低级烷基,R 4和R 5与它们所连接的氮原子一起形成2〜4、4和5的总环原子的杂环。及其药学上可接受的盐。该化合物可用于治疗自身免疫性疾病和过敏反应。

著录项

  • 公开/公告号NL7504588A

    专利类型

  • 公开/公告日1975-10-24

    原文格式PDF

  • 申请/专利号NL19750004588

  • 发明设计人

    申请日1975-04-17

  • 分类号C07C65/20;A61K31/40;A61K31/19;A61K31/44;A61K31/21;

  • 国家 NL

  • 入库时间 2022-08-23 04:35:13

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