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intermediate products intended for framstellning of alkoxilerade steroids
intermediate products intended for framstellning of alkoxilerade steroids
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机译:拟用于阿尔克西雷德类固醇的星状中间体产品
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摘要
11 alpha -ALKOXYLATED STEROIDS HAVING THE FORMULA WHEREIN R is alkyl having one to three carbon atoms, X represents a member selected from the group consisting of hydrogen, aliphatic hydrocarbon having one to six carbon atoms, halogenated aliphatic hydrocarbon having one to six carbon atoms, and cycloalkyl having three to six carbon atoms, Y is alkyl having one to six carbon atoms, Z represents a member selected from the group consisting of hydrogen, alkyl having one to six carbon atoms and phenyl alkyl having seven to nine carbon atoms, and R' represents a member selected from the group consisting of hydrogen and the acyl of an organic carboxylic acid having from one to 18 carbon atoms; as well as a process for preparing the compounds, therapeutic compositions and methods. The 11 alpha -alkoxylated steroids possess anti-estrogenic, anti-gonadotrophic and exogenic anti-androgenic activity.
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