Procedure for the preparation of dibenciletilinodyamine salt of the acid 6- (d-2-amino-2-phenylacetamido) -3,3-dimethyl-7-oxo-4-thio-1-azabiciclo (3,2,0) -heptane- 2-carboxilico little soluble in water and active tera. (Machine-translation by Google Translate, not legally binding)

摘要

Preparation procedure for the 6- (D-2-amino-2-phenylacetamido) -3,3-dimethyl-7-oxo-4-thio-1-azabicyclo (3.2.0.) Heptane-2-dibenzylethylenediamine salt Carboxylic, slightly soluble in water and therapeutically active, characterized by reacting a diamine base, dibenzylethylenediamine in aqueous suspension, in the proportion of one mole, with two moles of D-(-) α-aminobenzylpenicilinic acid trihydrate until the pH reach 7.2-7.3 with subsequent concentration, under reduced pressure of the solution containing the compound formed in the reaction and subsequent cooling of the concentrate thereof, whereby crystalline is separated into di-D-(-) α-aminobenzylpenicilinate of dibenzylethylenediamine (dibenzylethylene diamine ampicillinate). (Machine-translation by Google Translate, not legally binding)