Karubamiruguanijinsatsukinkagobutsu

摘要

Antimicrobial compounds are disclosed having the formula: P P Z--B--Y--B'--Z .nHAPPwherein B is carbamylguaidino, or thiocarbamylguanidino and B' is B or biguanidino provided that B' is biguanidino only when B is carbamylguanidino bonded to Y through the guanidino portion of the group, Y is a bivalent organic radical selected from the group consisting of C.sub.2 -C.sub.12 alkylene, C.sub.5 -C.sub. 12 cycloalkylene, C.sub.5 -C.sub.12 cycloalkylenebis(loweralkyl), C.sub.6 -C.sub.12 arylene and loweralkylarylene, C.sub.7 -C.sub.12 aryleneloweralkyl, and C.sub.8 -C. sub.12 arylenebis(loweralkyl) and Z is selected from the group consisting of C. sub.1 -C.sub.12 alkyl; C.sub.4 -C. sub.12 dialkylaminoalkyl; C.sub.3 -C.sub.12 alkenyl; C.sub.3 -C.sub.12 alkynyl; C.sub.3 -C.sub.12 cycloalkyl, C.sub.4 -C.sub.12 cycloalkylalkyl; C.sub.1 -C.sub.10 alkoxy C. sub.10 -C.sub.2 alkyl having a total carbon content of C.sub.3 -C.sub.14 ; C.sub.1 -C.sub.10 alkylthio C.sub.10 -C. sub.2 alkyl having a total carbon content of C.sub. 3 -C.sub.14 ; phenoxy C.sub.2 - C.sub.6 alkyl; phenylthio C.sub.2 -C.sub.6 alkyl; C.sub.6 -C. sub.14 aryl; C.sub.7 -C. sub.14 aralkyl and arylcycloalkyl; and C.sub.6 -C. sub.14 aryl and aralkyl substituted with one or more radicals selected from the group consisting of loweralkyl, trifluoromethyl, loweralkoxy, trifluoromethoxy, phenoxy, loweralkylthio, halo, nitro, cyano, C.sub.2 -C. sub.6 acyl, benzoyl, alkoxycarbonyl, diloweralkylamino, loweralkylsulfonyl, fluorosulfonyl and alkylsulfinyl; n=0, 1/3, 1/2, 2/3, 1, 2 and HA is an inorganic or organic acid.