Buredonisoronoyobiburedonisonjudotai

摘要

There is disclosed 16 alpha-methyl-17 alpha-bromo-1,4-pregnadiene-21-ol-3,20-dione-type compounds of the formula IMAGE where R is hydrogen or acyl; X is hydrogen, bromine, or fluorine; Y is hydrogen or oxygen; and Z is hydrogen or alpha - or beta -oriented fluorine. The compounds are useful in treating rheumatoid arthritis and related inflammatory disorders as well as allergic diseases.