Gasukuromatogurafuyokogakukatsuseikaramujutenzai

摘要

1519263 Gas chromatography SUMITOMO CHEMICAL CO Ltd 25 Feb 1976 [26 Feb 1975] 7477/76 Heading B1H [Also in Division C2] Compounds of formula:- having at least one asymmetric carbon atom wherein R 1 and R 2 are different and are each a hydrogen atom, an alkyl group having from 1 to 8 carbon atoms in the alkyl moiety or a phenyl group; R 3 is an alkyl group having from 1 to 12 carbon atoms, a cycloalkyl having 5 or 6 carbon atoms, an aralkyl group having 1 or 2 carbon atoms in the alkyl moiety thereof or a phenyl group; and X and Y are each independently one of the groups: wherein R 4 , R 5 , R 7 , R 8 and R 9 are each independently a hydrogen atom, an alkyl group having from 1 to 12 carbon atoms, a cycloalkyl group having 5 or 6 carbon atoms, an aralkyl group having 1 or 2 carbon atoms in the alkyl moiety thereof or a phenyl group; and R 6 is an alkyl group having from 1 to 12 carbon atoms, a cycloalkyl group having 5 or 6 carbon atoms, an aralkyl having 1 or 2 carbon atoms in the alkyl moiety thereof or a phenyl group, are used as the stationary phase in a gas chromatographic column for the resolution or analysis of a mixture of enantiomers having an -NH- group linked to an asymmetric carbon atom or to an atom in a position α to an asymmetric carbon atom. The Examples describe the separation of N- trifluoracetyl - d - alamine t - butyl ester and the corresponding l - ester from the dl mixture, N - trifluoroacetyl - d - α - phenethyamine and the corresponding l - amine from the dl mixture, and N - pentafluoropropionyl - d - α - naphthylethylamine and the corresponding l - amine from the dl - mixture.